Application
PDE8B Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PDE8B antibody detected the PDE8B protein (arrow).| Product Name | PDE8B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDE8B; High affinity cAMP-specific and IBMX-insensitive 3', 5'-cyclic phosphodiesterase 8B; Cell proliferation-inducing gene 22 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PDE8B High affinity cAMP-specific and IBMX-insensitive 3' 5'-cyclic phosphodiesterase 8B Cell proliferation-inducing gene 22 protein |
|---|---|
| Molecular Weight(MW) | 98979 Da |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in specific signaling in the thyroid gland |
| Tissue Specificity | Abundantly expressed in the thyroid. Also very weakly expressed in brain, spinal cord and placenta. In the thyroid isoform 1 predominates, and isoforms 2 and 6 are also highly expressed. In the placenta isoforms 1 and 2 are expressed equally. In the brain isoform 2 predominates |
| Entrez Gene | 8622 |
|---|---|
| Nucleotide Accession | NP_003710.1 |
Application
PDE8B Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PDE8B antibody detected the PDE8B protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
