Application
PDS5A Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PDS5A antibody detected the PDS5A protein (arrow).| Product Name | PDS5A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDS5A; KIAA0648; PDS5; Sister chromatid cohesion protein PDS5 homolog A; Cell proliferation-inducing gene 54 protein; Sister chromatid cohesion protein 112 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0648 PDS5 |
|---|---|
| Alternative Names | PDS5A KIAA0648 PDS5 Sister chromatid cohesion protein PDS5 homolog A Cell proliferation-inducing gene 54 protein Sister chromatid cohesion protein 112 |
| Molecular Weight(MW) | 150830 Da |
| Function | Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair |
| Tissue Specificity | Highest level in colon. Low levels in lung, ovary, breast and kidney. Reduced level in renal tumor tissue Isoform 2 is expressed in kidney |
| Cellular Localization | Nucleus. Note=Associated with chromatin through most of the cell cycle. Dissociates from chromatin in late prophase, reassociates during late telophase |
| Entrez Gene | 23244 |
|---|---|
| Nucleotide Accession | NP_001093869.1 NP_001093870.1 |
Application
PDS5A Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PDS5A antibody detected the PDS5A protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
