Application
PDZD3 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PDZD3 antibody detected the PDZD3 protein (arrow).| Product Name | PDZD3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDZD3; IKEPP; NHERF4; PDZK2; Na(+)/H(+) exchange regulatory cofactor NHE-RF4; Intestinal and kidney-enriched PDZ protein; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2; PDZ domain-containing protein 2; PDZ domain-containing protein 3; |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IKEPP NHERF4 PDZK2 |
|---|---|
| Alternative Names | PDZD3 IKEPP NHERF4 PDZK2 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 Intestinal and kidney-enriched PDZ protein Natrium-phosphate cotransporter IIa C-terminal-associated protein 2 PDZ domain-containing protein 2 PDZ domain-containing protein 3 |
| Molecular Weight(MW) | 61032 Da |
| Function | Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions |
| Tissue Specificity | Expressed in kidney and the gastrointestinal tract. Not detected in brain, heart, skeletal muscle or cells of hematopoietic origin |
| Cellular Localization | Cell membrane; Peripheral membrane protein. Cytoplasm. Note=Preferentially accumulates at the apical surface and ileal brush border of intestinal epithelial cells |
| Entrez Gene | 79849 |
|---|---|
| Nucleotide Accession | NP_001161940.1 NP_079067.3 |
Application
PDZD3 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PDZD3 antibody detected the PDZD3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
