Application
PEAR1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PEAR1 antibody detected the PEAR1 protein (arrow).Application
PEAR1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PEAR1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PEAR1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PEAR1; MEGF12; Platelet endothelial aggregation receptor 1; Multiple epidermal growth factor-like domains protein 12 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MEGF12 |
|---|---|
| Alternative Names | PEAR1 MEGF12 Platelet endothelial aggregation receptor 1 Multiple epidermal growth factor-like domains protein 12 |
| Molecular Weight(MW) | 110666 Da |
| Function | When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity) |
| Tissue Specificity | Expressed in umbilical vein endothelial cells and platelets (at protein level). Expressed in heart, kidney, skeletal muscle, pancreas, ovary, breast, lung, brain cortex, hypothalamus, spinal cord, dorsal root ganglion, endothelial cells of umbilical cord artery and vein, megakaryocytes, osteoblasts, coronary muscle and erythroid cells. Weakly expressed in peripheral blood leukocytes and macrophages |
| Cellular Localization | Cell membrane; Single-pass membrane protein (Potential). Note=Detected on the cell surface in resting platelets |
| Entrez Gene | 375033 |
|---|---|
| Nucleotide Accession | NP_001073940.1 |
Application
PEAR1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PEAR1 antibody detected the PEAR1 protein (arrow).
Application
PEAR1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PEAR1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
