Application
PELI1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PELI1 antibody detected the PELI1 protein (arrow).| Product Name | PELI1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PELI1; PRISM; E3 ubiquitin-protein ligase pellino homolog 1; Pellino-related intracellular-signaling molecule |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PRISM |
|---|---|
| Alternative Names | PELI1 PRISM E3 ubiquitin-protein ligase pellino homolog 1 Pellino-related intracellular-signaling molecule |
| Molecular Weight(MW) | 46286 Da |
| Function | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation |
| Tissue Specificity | This PELI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 176-204 amino acids selected from the Central region of human PELI1. |
| Entrez Gene | 57162 |
|---|---|
| Nucleotide Accession | NP_065702.2 |
Application
PELI1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PELI1 antibody detected the PELI1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
