Application
PENK Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PENK antibody detected the PENK protein (arrow).Application
PENK antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PENK antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
PENK Antibody (Center) flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | PENK Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PENK; Proenkephalin-A; Synenkephalin; Met-enkephalin; Opioid growth factor; PENK(114-133); PENK(143-183); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; PENK(237-258); Met-enkephalin-Arg-Phe |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PENK Proenkephalin-A Synenkephalin Met-enkephalin Opioid growth factor PENK(114-133) PENK(143-183) Met-enkephalin-Arg-Gly-Leu Leu-enkephalin PENK(237-258) Met-enkephalin-Arg-Phe |
|---|---|
| Molecular Weight(MW) | 30787 Da |
| Function | Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum |
| Tissue Specificity | This PENK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-182 amino acids from the Central region of human PENK. |
| Cellular Localization | Secreted. |
| Entrez Gene | 5179 |
|---|---|
| Nucleotide Accession | NP_001129162.1 NP_006202.1 |
Application
PENK Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PENK antibody detected the PENK protein (arrow).
Application
PENK antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PENK antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
PENK Antibody (Center) flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
