Application
PFN2 Antibody (C-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the PFN2 antibody detected the PFN2 protein (arrow).| Product Name | PFN2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PFN2; Profilin-2; Profilin II |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PFN2 Profilin-2 Profilin II |
|---|---|
| Molecular Weight(MW) | 15046 Da |
| Function | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG |
| Tissue Specificity | Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Entrez Gene | 5217 |
|---|---|
| Nucleotide Accession | NP_444252.1 NP_002619.1 |
Application
PFN2 Antibody (C-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the PFN2 antibody detected the PFN2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
