Application
PGF Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PGF antibody detected the PGF protein (arrow).Application
PGF Antibody (Center) (AP14578c)immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PGF Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PGF Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PGF; PGFL; PLGF; Placenta growth factor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PGFL PLGF |
|---|---|
| Alternative Names | PGF PGFL PLGF Placenta growth factor |
| Molecular Weight(MW) | 24789 Da |
| Function | Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth |
| Tissue Specificity | While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas |
| Cellular Localization | Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin |
| Entrez Gene | 5228 |
|---|---|
| Nucleotide Accession | NP_002623.2 |
Application
PGF Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PGF antibody detected the PGF protein (arrow).
Application
PGF Antibody (Center) (AP14578c)immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PGF Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
