PGLYRP4 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PGLYRP4 antibody detected the PGLYRP4 protein (arrow).
PGLYRP4; PGRPIB; Peptidoglycan recognition protein 4; Peptidoglycan recognition protein I-beta; Peptidoglycan recognition protein intermediate beta
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
PGRPIB
Alternative Names
PGLYRP4 PGRPIB Peptidoglycan recognition protein 4 Peptidoglycan recognition protein I-beta Peptidoglycan recognition protein intermediate beta
Molecular Weight(MW)
40620 Da
Function
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity
Tissue Specificity
Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus
PGLYRP4 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PGLYRP4 antibody detected the PGLYRP4 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.