Application
PHF12 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the PHF12 antibody detected the PHF12 protein (arrow).Application
PHF12 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PHF12 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PHF12 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PHF12; KIAA1523; PHD finger protein 12; PHD factor 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1523 |
|---|---|
| Alternative Names | PHF12 KIAA1523 PHD finger protein 12 PHD factor 1 |
| Molecular Weight(MW) | 109698 Da |
| Function | Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA |
| Tissue Specificity | This PHF12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 838-866 amino acids from the C-terminal region of human PHF12. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 57649 |
|---|---|
| Nucleotide Accession | NP_001028733.1 NP_065940.1 |
Application
PHF12 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the PHF12 antibody detected the PHF12 protein (arrow).
Application
PHF12 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PHF12 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
