Application
PHF17 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PHF17 antibody detected the PHF17 protein (arrow).Application
PHF17 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PHF17 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PHF17 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PHF17; JADE1; KIAA1807; Protein Jade-1; PHD finger protein 17 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | JADE1 KIAA1807 |
|---|---|
| Alternative Names | PHF17 JADE1 KIAA1807 Protein Jade-1 PHD finger protein 17 |
| Molecular Weight(MW) | 95533 Da |
| Function | Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor |
| Tissue Specificity | Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level). Down-regulated in renal cancer cells |
| Cellular Localization | Cytoplasm. Nucleus. |
| Entrez Gene | 79960 |
|---|---|
| Nucleotide Accession | NP_079176.2 |
Application
PHF17 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PHF17 antibody detected the PHF17 protein (arrow).
Application
PHF17 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PHF17 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
