Application
PHF20 Antibody (N-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the PHF20 antibody detected the PHF20 protein (arrow).Application
PHF20 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PHF20 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PHF20 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PHF20; C20orf104; GLEA2; HCA58; NZF; TZP; PHD finger protein 20; Glioma-expressed antigen 2; Hepatocellular carcinoma-associated antigen 58; Novel zinc finger protein; Transcription factor TZP |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C20orf104 GLEA2 HCA58 NZF TZP |
|---|---|
| Alternative Names | PHF20 C20orf104 GLEA2 HCA58 NZF TZP PHD finger protein 20 Glioma-expressed antigen 2 Hepatocellular carcinoma-associated antigen 58 Novel zinc finger protein Transcription factor TZP |
| Molecular Weight(MW) | 115386 Da |
| Function | Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage |
| Tissue Specificity | Expressed in heart, kidney, liver, lung, pancreas, placenta, spleen and testis. Not expressed in brain, skeletal muscle, colon, ovary, prostate, small intestine and thymus. Expressed in colon and ovary cancer cell lines while it is not expressed in the respective normal tissues |
| Cellular Localization | Nucleus. |
| Entrez Gene | 51230 |
|---|---|
| Nucleotide Accession | NP_057520.2 |
Application
PHF20 Antibody (N-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the PHF20 antibody detected the PHF20 protein (arrow).
Application
PHF20 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PHF20 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
