Application
Dot blot analysis of Phospho-FLNA-S2152 Antibody and FLNA Non Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.| Product Name | Phospho-FLNA-S2152 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification | p-S2152 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | DB |
| DB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FLN, FLN1 |
|---|---|
| Alternative Names | FLNA FLN FLN1 Filamin-A Actin-binding protein 280 Alpha-filamin Endothelial actin-binding protein Filamin-1 Non-muscle filamin |
| Molecular Weight(MW) | 280739 Da |
| Function | Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm, cell cortex. Cytoplasm, cytoskeleton |
| Entrez Gene | 2316 |
|---|
Application
Dot blot analysis of Phospho-FLNA-S2152 Antibody and FLNA Non Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.| Application Notes | DB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein A affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
