Application
A. Western blot analysis on HeLa cell lysates using anti-Phospho-Filamin A (pS1458) RabMAb (Cat. #AJ1299b), 1:5000 dilution. Cells were either (A) untreated (B) treated with APApplication
B. Immunohistochemical analysis of paraffin-embedded human stomach using Phospho-specific anti-Filamin A RabMAb (Cat. #AJ1299b)Application
C. Immunohistochemical analysis of paraffin-embedded human uterus using Phospho-specific anti-Filamin A RabMAb (Cat. #AJ1299b).| Product Name | Filamin-A Antibody Phospho (pS1458) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification | p-S1458 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP2309Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:5000~20000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FLN, FLN1 |
|---|---|
| Molecular Weight(MW) | 280739 Da |
| Function | Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm, cell cortex. Cytoplasm, cytoskeleton |
| Entrez Gene | 2316 |
|---|
Application
A. Western blot analysis on HeLa cell lysates using anti-Phospho-Filamin A (pS1458) RabMAb (Cat. #AJ1299b), 1:5000 dilution. Cells were either (A) untreated (B) treated with AP
Application
B. Immunohistochemical analysis of paraffin-embedded human stomach using Phospho-specific anti-Filamin A RabMAb (Cat. #AJ1299b)
Application
C. Immunohistochemical analysis of paraffin-embedded human uterus using Phospho-specific anti-Filamin A RabMAb (Cat. #AJ1299b).| Application Notes | WB:1:5000~20000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
