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Phospho-KRT19-pS46 Antibody

Catalog Number:OM217442
OM217442
Discount Price
OM217442-100ul
1~2 Week
100ul
OM217442-50ul
50ul
OM217442-20ul
20ul
1~2 Week
Product Profile
Product Name Phospho-KRT19-pS46 Antibody
Antibody Type Primary Antibodies
Modification p-S46
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications DBIF
DB:1:500 IF
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names KRT19
Keratin
type I cytoskeletal 19
Cytokeratin-19
Keratin-19
Molecular Weight(MW) 44106 Da
Function Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle
Tissue Specificity Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin
Database Links
Entrez Gene 3880
Application

Application

Dot blot analysis of anti-Phospho-KRT19-pS46 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Application

Confocal immunofluorescent analysis of Phospho-KRT19-pS46 Antibody(Cat#AP3631a) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Application Notes DB:1:500 IF
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
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