Application
The anti-Phospho-LLGL1/2 Pab is used for detection against A2058 cell line lysate. Phospho-LLGL1/2(arrow) was detected using the purified Pab.| Product Name | Phospho-LLGL1/2-S645/S649 (LLGL2) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification | p-S645/S649 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | LLGL2 Lethal(2) giant larvae protein homolog 2 HGL |
|---|---|
| Molecular Weight(MW) | 113448 Da |
| Function | Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity |
| Tissue Specificity | This Phospho-LLGL1/2-S645/S649 (LLGL2) antibody is generated from rabbits immunized with a KLH conjugated synthetic diphosphopeptide corresponding to amino acid residues surrounding S645 and S649 of human LLGL1/2. |
| Cellular Localization | Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells |
| Entrez Gene | 3993 |
|---|
Application
The anti-Phospho-LLGL1/2 Pab is used for detection against A2058 cell line lysate. Phospho-LLGL1/2(arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein G affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
