Application
Dot blot analysis of Phospho-mouse BAD-S112 Antibody Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.| Product Name | Phospho-mouse BAD-S112 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Bad; Bbc6; Bcl2 antagonist of cell death; Bcl-2-binding component 6; Bcl-xL/Bcl-2-associated death promoter |
| Modification | p-S112 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | DB |
| DB:1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Bbc6 |
|---|---|
| Alternative Names | Bad Bbc6 Bcl2 antagonist of cell death Bcl-2-binding component 6 Bcl-xL/Bcl-2-associated death promoter |
| Molecular Weight(MW) | 22080 Da |
| Function | Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 Appears to act as a link between growth factor receptor signaling and the apoptotic pathways |
| Tissue Specificity | This Phospho-mouse BAD-S112 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S112 of mouse BAD. |
| Cellular Localization | Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm |
| Entrez Gene | 12015 |
|---|---|
| Nucleotide Accession | NP_031548.1 |
Application
Dot blot analysis of Phospho-mouse BAD-S112 Antibody Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.| Application Notes | DB:1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
