Application
PHOX2B Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PHOX2B antibody detected the PHOX2B protein (arrow).| Product Name | PHOX2B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PHOX2B; PMX2B; Paired mesoderm homeobox protein 2B; Neuroblastoma Phox; PHOX2B homeodomain protein; Paired-like homeobox 2B |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PMX2B |
|---|---|
| Alternative Names | PHOX2B PMX2B Paired mesoderm homeobox protein 2B Neuroblastoma Phox PHOX2B homeodomain protein Paired-like homeobox 2B |
| Molecular Weight(MW) | 31621 Da |
| Function | Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum- response element |
| Tissue Specificity | Expressed in neuroblastoma, brain and adrenal gland |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 8929 |
|---|---|
| Nucleotide Accession | NP_003915.2 |
Application
PHOX2B Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PHOX2B antibody detected the PHOX2B protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
