Application
PI4K2A Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PI4K2A antibody detected the PI4K2A protein (arrow).| Product Name | PI4K2A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PI4K2A; Phosphatidylinositol 4-kinase type 2-alpha; Phosphatidylinositol 4-kinase type II-alpha |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PI4K2A Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type II-alpha |
|---|---|
| Molecular Weight(MW) | 54022 Da |
| Function | Together with PI4K2B and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells (By similarity) |
| Tissue Specificity | Widely expressed. Highest expression is observed in kidney, brain, heart, skeletal muscle, and placenta and lowest expression is observed in colon, thymus, and small intestine |
| Cellular Localization | Cytoplasm. Membrane (By similarity). Membrane raft. Cell projection, dendrite (By similarity). Cell junction, synapse, presynaptic cell membrane (By similarity). Cell junction, synapse, synaptosome (By similarity). Mitochondrion (By similarity). Endosome (By similarity). Cytoplasmic vesicle (By similarity). Note=Localized in neuronal cell body. Transported from neuronal cell body to neuron projections in a BLOC-1- and AP- 3-complexes-dependent manner. Enriched in neurite tips and neuron projections in a BLOC-1- and AP-3-complexes-dependent manner (By similarity). Found in subdomains of the plasma membrane termed non-caveolar membrane rafts |
| Entrez Gene | 55361 |
|---|---|
| Nucleotide Accession | NP_060895.1 |
Application
PI4K2A Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PI4K2A antibody detected the PI4K2A protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
