Application
Western blot analysis of hPRKCABP-C300 in HL-60, Jurkat, K562 cell line lysates (35ug/lane). PRKCABP (arrow) was detected using the purified Pab.| Product Name | PICK1 (PRKCABP) Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PICK1; PRKCABP; PRKCA-binding protein; Protein interacting with C kinase 1; Protein kinase C-alpha-binding protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PRKCABP |
|---|---|
| Alternative Names | PICK1 PRKCABP PRKCA-binding protein Protein interacting with C kinase 1 Protein kinase C-alpha-binding protein |
| Molecular Weight(MW) | 46600 Da |
| Function | Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ASIC1/ASIC3 channel |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm, perinuclear region. Cell junction, synapse. Note=Also present at excitatory synapses |
| Entrez Gene | 9463 |
|---|
Application
Western blot analysis of hPRKCABP-C300 in HL-60, Jurkat, K562 cell line lysates (35ug/lane). PRKCABP (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
