Application
PIPPIN Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PIPPIN antibody detected the PIPPIN protein (arrow).Application
PIPPIN Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PIPPIN Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PIPPIN Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CSDC2; PIPPIN; Cold shock domain-containing protein C2; RNA-binding protein PIPPin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PIPPIN |
|---|---|
| Alternative Names | CSDC2 PIPPIN Cold shock domain-containing protein C2 RNA-binding protein PIPPin |
| Molecular Weight(MW) | 16786 Da |
| Function | RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity) |
| Tissue Specificity | This PIPPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-105 amino acids from the Central region of human PIPPIN. |
| Cellular Localization | Nucleus (By similarity). Cytoplasm (By similarity). Note=PIPPin-RNA complexes are located to the nucleus (By similarity) |
| Entrez Gene | 27254 |
|---|---|
| Nucleotide Accession | NP_055275.1 |
Application
PIPPIN Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PIPPIN antibody detected the PIPPIN protein (arrow).
Application
PIPPIN Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PIPPIN Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
