Application
PJA2 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PJA2 antibody detected the PJA2 protein (arrow).| Product Name | PJA2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PJA2; KIAA0438; RNF131; E3 ubiquitin-protein ligase Praja-2; RING finger protein 131 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0438 RNF131 |
|---|---|
| Alternative Names | PJA2 KIAA0438 RNF131 E3 ubiquitin-protein ligase Praja-2 RING finger protein 131 |
| Molecular Weight(MW) | 78214 Da |
| Function | Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes |
| Tissue Specificity | This PJA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the Central region of human PJA2. |
| Cellular Localization | Cytoplasm. Cell membrane. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cell junction, synapse (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Note=Localizes at the cytoplasmic side of endoplasmic reticulum and Golgi apparatus Expressed in the postsynaptic density region of synapses (By similarity). Co-localizes with PRKAR2A and PRKAR2B in the cytoplasm and the cell membrane |
| Entrez Gene | 9867 |
|---|---|
| Nucleotide Accession | NP_055634.3 |
Application
PJA2 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PJA2 antibody detected the PJA2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
