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PKA 2 beta (PRKAR2B) Antibody (N-term)

Catalog Number:OM217995
OM217995
Discount Price
OM217995-100ul
1~2 Week
100ul
OM217995-50ul
50ul
OM217995-20ul
20ul
1~2 Week
Product Profile
Product Name PKA 2 beta (PRKAR2B) Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias PRKAR2B; cAMP-dependent protein kinase type II-beta regulatory subunit
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names PRKAR2B
cAMP-dependent protein kinase type II-beta regulatory subunit
Molecular Weight(MW) 46302 Da
Function Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase
Tissue Specificity Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible
Cellular Localization Cytoplasm. Cell membrane. Note=Co-localizes with PJA2 in the cytoplasm and at the cell membrane
Database Links
Entrez Gene 5577
Application

Application

Western blot analysis of anti-PRKAR2B Pab in mouse brain tissue lysate. PRKAR2B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Application

Western blot analysis of PRKAR2B (arrow) using rabbit polyclonal PRKAR2B Antibody (G46) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRKAR2B gene.

Application

PRKAR2B Antibody (G46) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the PRKAR2B antibody detected the PRKAR2B protein (arrow).
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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