Application
A. Western blot analysis on fetal brain lysates using anti-Phospho-PKA RIIb (pS114) RabMAb (Cat. #AJ1613b). Cells were either (A) untreated (B) treated with LP| Product Name | PKA RIIb Antibody Phospho (pS114) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PRKAR2B, cAMP-dependent protein kinase type II-beta regulatory subunit |
| Modification | p-S114 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP2607 |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000~2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PRKAR2B cAMP-dependent protein kinase type II-beta regulatory subunit |
|---|---|
| Molecular Weight(MW) | 46302 Da |
| Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase |
| Tissue Specificity | Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible |
| Cellular Localization | Cytoplasm. Cell membrane. Note=Co-localizes with PJA2 in the cytoplasm and at the cell membrane |
| Entrez Gene | 5577 |
|---|
Application
A. Western blot analysis on fetal brain lysates using anti-Phospho-PKA RIIb (pS114) RabMAb (Cat. #AJ1613b). Cells were either (A) untreated (B) treated with LP| Application Notes | WB:1:1000~2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
