Application
Western blot analysis of PKHH2 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). PKHH2 (arrow) was detected using the purified Pab.Application
PKHH2 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APKHH2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
PKHH2 Antibody (C-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | PKHH2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PLEKHH2; KIAA2028; Pleckstrin homology domain-containing family H member 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA2028 |
|---|---|
| Alternative Names | PLEKHH2 KIAA2028 Pleckstrin homology domain-containing family H member 2 |
| Molecular Weight(MW) | 168229 Da |
| Function | In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia |
| Tissue Specificity | Kidney. Reduced expression in patients with focal segmental glomerulosclerosis |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Note=Localizes to foot process of podocytes. Localization to peripheral regions of lamellipodia seems to be dependent on PI3K |
| Entrez Gene | 130271 |
|---|
Application
Western blot analysis of PKHH2 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). PKHH2 (arrow) was detected using the purified Pab.
Application
PKHH2 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APKHH2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
PKHH2 Antibody (C-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
