Application
PLCD3 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PLCD3 antibody detected the PLCD3 protein (arrow).| Product Name | PLCD3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PLCD3; KIAA1964; 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase delta-3; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1964 |
|---|---|
| Alternative Names | PLCD3 KIAA1964 1-phosphatidylinositol 4 5-bisphosphate phosphodiesterase delta-3 Phosphoinositide phospholipase C-delta-3 Phospholipase C-delta-3 |
| Molecular Weight(MW) | 89258 Da |
| Function | Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow |
| Tissue Specificity | Present in corneal epithelial cells (at protein level) |
| Cellular Localization | Membrane; Peripheral membrane protein. Cytoplasm. Cleavage furrow. Note=Localizes at the cleavage furrow during cytokinesis |
| Entrez Gene | 113026 |
|---|---|
| Nucleotide Accession | NP_588614.1 |
Application
PLCD3 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PLCD3 antibody detected the PLCD3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
