Application
Western blot analysis of PLCL1 Antibody (N-term) in Jurkat cell line lysates (35ug/lane). PLCL1 (arrow) was detected using the purified Pab.Application
PLCL1 Antibody (N-term) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | PLCL1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PLCL1; Inactive phospholipase C-like protein 1; Phospholipase C-deleted in lung carcinoma; Phospholipase C-related but catalytically inactive protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100-500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PLCL1 Inactive phospholipase C-like protein 1 Phospholipase C-deleted in lung carcinoma Phospholipase C-related but catalytically inactive protein |
|---|---|
| Molecular Weight(MW) | 122728 Da |
| Function | Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C |
| Tissue Specificity | Expressed in a variety of fetal and adult organs including brain, lung and kidney. Its expression was greatly reduced in small and non-small cell lung carcinoma Isoform 1 is predominantly expressed in brain |
| Cellular Localization | Cytoplasm (By similarity). |
| Entrez Gene | 5334 |
|---|
Application
Western blot analysis of PLCL1 Antibody (N-term) in Jurkat cell line lysates (35ug/lane). PLCL1 (arrow) was detected using the purified Pab.
Application
PLCL1 Antibody (N-term) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100-500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
