Application
A. Western blot analysis on Jurkat cell lysate using anti-Plectin RabMAb (Cat. #AJ1635a), dilution 1:5,000.Application
B. Immunohistochemical staining of paraffin-embedded human skeletal muscle using anti-Plectin RabMAb (Cat. #AJ1635a).| Product Name | Plectin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PLEC1, Plectin-1, Hemidesmosomal protein 1 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | E398P |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~10000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PLEC1 |
|---|---|
| Alternative Names | PLEC1 Plectin-1 Hemidesmosomal protein 1 |
| Molecular Weight(MW) | 531791 Da |
| Function | Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofibers integrity |
| Tissue Specificity | Widely expressed with highest levels in muscle, heart, placenta and spinal cord |
| Cellular Localization | Cytoplasm, cytoskeleton. Cell junction, hemidesmosome |
| Entrez Gene | 5339 |
|---|
Application
A. Western blot analysis on Jurkat cell lysate using anti-Plectin RabMAb (Cat. #AJ1635a), dilution 1:5,000.
Application
B. Immunohistochemical staining of paraffin-embedded human skeletal muscle using anti-Plectin RabMAb (Cat. #AJ1635a).| Application Notes | WB:1:1000~10000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
