Application
A.Western blot analysis on lysates (A) NIH/3T3 treated with 2% FBS cell lysate and (B) fetal brain tissue lysate using anti-pleiotrophin RabMAb (Cat. #AJ1636a), dilution 1:20,000.| Product Name | Pleiotrophin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTN, HBNF1, NEGF1, Pleiotrophin, Heparin-binding brain mitogen |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3041 |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:10000~20000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HBNF1 NEGF1 |
|---|---|
| Alternative Names | PTN HBNF1 NEGF1 Pleiotrophin Heparin-binding brain mitogen |
| Molecular Weight(MW) | 18942 Da |
| Function | Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti- apoptotic signaling of PTN and regulation of cell proliferation |
| Tissue Specificity | Osteoblast and brain. |
| Cellular Localization | Secreted. |
| Entrez Gene | 5764 |
|---|
Application
A.Western blot analysis on lysates (A) NIH/3T3 treated with 2% FBS cell lysate and (B) fetal brain tissue lysate using anti-pleiotrophin RabMAb (Cat. #AJ1636a), dilution 1:20,000.| Application Notes | WB:1:10000~20000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
