Application
PNPLA6 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PNPLA6 antibody detected the PNPLA6 protein (arrow).| Product Name | PNPLA6 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NTE |
|---|---|
| Alternative Names | PNPLA6 NTE Neuropathy target esterase Patatin-like phospholipase domain-containing protein 6 |
| Molecular Weight(MW) | 149995 Da |
| Function | Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy |
| Tissue Specificity | Expressed in brain, placenta, kidney, neuron and skeletal muscle |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein; Cytoplasmic side. Note=Anchored to the cytoplasmic face of the endoplasmic reticulum by its amino- terminal transmembrane segment |
| Entrez Gene | 10908 |
|---|---|
| Nucleotide Accession | NP_001159583.1 NP_001159585.1 |
Application
PNPLA6 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PNPLA6 antibody detected the PNPLA6 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
