Application
A. Western blot analysis on Jurkat cell lysate using anti-PP1 beta RabMAb (Cat. #AJ1643a).Application
B. Immunohistochemical analysis of paraffin-embedded human muscle using anti-PP1 beta RabMAb (Cat. #AJ1643a).| Product Name | PP1 beta Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPP1CB, Serine/threonine-protein phosphatase PP1-beta catalytic subunit |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1804Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~5000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PPP1CB Serine/threonine-protein phosphatase PP1-beta catalytic subunit |
|---|---|
| Molecular Weight(MW) | 37187 Da |
| Function | Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase |
| Tissue Specificity | A synthetic peptide corresponding to residues on human PP1 beta was used as an immunogen. |
| Cellular Localization | Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles |
| Entrez Gene | 5500 |
|---|
Application
A. Western blot analysis on Jurkat cell lysate using anti-PP1 beta RabMAb (Cat. #AJ1643a).
Application
B. Immunohistochemical analysis of paraffin-embedded human muscle using anti-PP1 beta RabMAb (Cat. #AJ1643a).| Application Notes | WB:1:1000~5000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
