Application
The anti-PPM1D Pab is used in Western blot to detect PPM1D in 293 cell lysate.| Product Name | PPM1D Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPM1D; WIP1; Protein phosphatase 1D; Protein phosphatase 2C isoform delta; Protein phosphatase magnesium-dependent 1 delta; p53-induced protein phosphatase 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | WIP1 |
|---|---|
| Alternative Names | PPM1D WIP1 Protein phosphatase 1D Protein phosphatase 2C isoform delta Protein phosphatase magnesium-dependent 1 delta p53-induced protein phosphatase 1 |
| Molecular Weight(MW) | 66675 Da |
| Function | Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins |
| Tissue Specificity | This PPM1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576~605 amino acids from the C-terminal region of human PPM1D. |
| Entrez Gene | 8493 |
|---|
Application
The anti-PPM1D Pab is used in Western blot to detect PPM1D in 293 cell lysate.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
