Application
PPP1R10 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PPP1R10 antibody detected the PPP1R10 protein (arrow).Application
PPP1R10 Antibody (Center) (AP14051c)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PPP1R10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PPP1R10 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPP1R10; CAT53; FB19; PNUTS; Serine/threonine-protein phosphatase 1 regulatory subunit 10; MHC class I region proline-rich protein CAT53; PP1-binding protein of 114 kDa; Phosphatase 1 nuclear targeting subunit; Protein FB19; p99 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAT53 FB19 PNUTS |
|---|---|
| Alternative Names | PPP1R10 CAT53 FB19 PNUTS Serine/threonine-protein phosphatase 1 regulatory subunit 10 MHC class I region proline-rich protein CAT53 PP1-binding protein of 114 kDa Phosphatase 1 nuclear targeting subunit Protein FB19 p99 |
| Molecular Weight(MW) | 99058 Da |
| Function | Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity) |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas |
| Cellular Localization | Nucleus. Note=Found in discrete nucleoplasmic bodies and within nucleoli. Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase (By similarity) |
| Entrez Gene | 5514 |
|---|---|
| Nucleotide Accession | NP_002705.2 |
Application
PPP1R10 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PPP1R10 antibody detected the PPP1R10 protein (arrow).
Application
PPP1R10 Antibody (Center) (AP14051c)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PPP1R10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
