Application
PPP1R12A Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PPP1R12A antibody detected the PPP1R12A protein (arrow).| Product Name | PPP1R12A Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPP1R12A; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Protein phosphatase myosin-binding subunit |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MBS MYPT1 |
|---|---|
| Alternative Names | PPP1R12A MBS MYPT1 Protein phosphatase 1 regulatory subunit 12A Myosin phosphatase-targeting subunit 1 Protein phosphatase myosin-binding subunit |
| Molecular Weight(MW) | 115281 Da |
| Function | Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity |
| Tissue Specificity | Expressed in striated muscles, specifically in type 2a fibers (at protein level) |
| Cellular Localization | Cytoplasm. Note=Along actomyosin filaments and stress fibers |
| Entrez Gene | 4659 |
|---|---|
| Nucleotide Accession | NP_002471.1 |
Application
PPP1R12A Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PPP1R12A antibody detected the PPP1R12A protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
