Application
PPP1R13B Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the PPP1R13B antibody detected the PPP1R13B protein (arrow).| Product Name | PPP1R13B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPP1R13B; ASPP1; KIAA0771; Apoptosis-stimulating of p53 protein 1; Protein phosphatase 1 regulatory subunit 13B |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ASPP1 KIAA0771 |
|---|---|
| Alternative Names | PPP1R13B ASPP1 KIAA0771 Apoptosis-stimulating of p53 protein 1 Protein phosphatase 1 regulatory subunit 13B |
| Molecular Weight(MW) | 119565 Da |
| Function | Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo |
| Tissue Specificity | Reduced expression in breast carcinomas expressing a wild-type TP53 protein |
| Cellular Localization | Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Some fraction is nuclear |
| Entrez Gene | 23368 |
|---|---|
| Nucleotide Accession | NP_056131.2 |
Application
PPP1R13B Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the PPP1R13B antibody detected the PPP1R13B protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
