Application
Western blot analysis of anti-PPP6C Antibody (C-term) in Jurkat cell line lysates (35ug/lane). PPP6C(arrow) was detected using the purified Pab.Application
PPP6C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PPP6C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PPP6C Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPP6C; PPP6; Serine/threonine-protein phosphatase 6 catalytic subunit |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PPP6 |
|---|---|
| Alternative Names | PPP6C PPP6 Serine/threonine-protein phosphatase 6 catalytic subunit |
| Molecular Weight(MW) | 35144 Da |
| Function | Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7 |
| Tissue Specificity | Ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 5537 |
|---|
Application
Western blot analysis of anti-PPP6C Antibody (C-term) in Jurkat cell line lysates (35ug/lane). PPP6C(arrow) was detected using the purified Pab.
Application
PPP6C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PPP6C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
