RABAC1, PRA1, PRAF1, Prenylated Rab acceptor protein 1, PRA1 family protein 1
Key Feature
Clonality
Monoclonal
Clone Number
EPR1747Y
Host Species
Rabbit
Tested Applications
WB
WB:1:500~2000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
PRA1 PRAF1
Alternative Names
RABAC1 PRA1 PRAF1 Prenylated Rab acceptor protein 1 PRA1 family protein 1
Molecular Weight(MW)
20648 Da
Function
General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI (By similarity)
Tissue Specificity
Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach
Cellular Localization
Cell membrane; Multi-pass membrane protein (By similarity). Cytoplasm (By similarity). Golgi apparatus (By similarity). Cytoplasmic vesicle, secretory vesicle, synaptic vesicle (By similarity). Note=According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles (By similarity)