Application
PRICKLE1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PRICKLE1 antibody detected the PRICKLE1 protein (arrow).| Product Name | PRICKLE1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PRICKLE1; RILP; Prickle-like protein 1; REST/NRSF-interacting LIM domain protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RILP |
|---|---|
| Alternative Names | PRICKLE1 RILP Prickle-like protein 1 REST/NRSF-interacting LIM domain protein 1 |
| Molecular Weight(MW) | 94300 Da |
| Function | Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis Necessary for nuclear localization of REST. May serve as nuclear receptor |
| Tissue Specificity | Expressed at highest levels in placenta and at lower levels in lung, liver, kidney and pancreas. Expressed in thalamus, hippocampus, cerebral cortex, and cerebellum (in neurons rather than glia) |
| Cellular Localization | Nucleus membrane. Cytoplasm, cytosol. Note=A smaller amount is detected in the cytosol |
| Entrez Gene | 144165 |
|---|---|
| Nucleotide Accession | NP_001138353.1 |
Application
PRICKLE1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PRICKLE1 antibody detected the PRICKLE1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
