PTP4A1; PRL1; PTPCAAX1; Protein tyrosine phosphatase type IVA 1; PTP(CAAXI); Protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
PRL1 PTPCAAX1
Alternative Names
PTP4A1 PRL1 PTPCAAX1 Protein tyrosine phosphatase type IVA 1 PTP(CAAXI) Protein-tyrosine phosphatase 4a1 Protein-tyrosine phosphatase of regenerating liver 1
Molecular Weight(MW)
19815 Da
Function
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis
Tissue Specificity
Expressed in bone marrow, lymph nodes, T lymphocytes, spleen, thymus and tonsil. Overexpressed in tumor cell lines
Western blot analysis of PRL1 in mouse spleen tissue lysates (35ug/lane). PRL1 Antibody (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.