PRPF6 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PRPF6 antibody detected the PRPF6 protein (arrow).
PRPF6; C20orf14; Pre-mRNA-processing factor 6; Androgen receptor N-terminal domain-transactivating protein 1; PRP6 homolog; U5 snRNP-associated 102 kDa protein
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
C20orf14
Alternative Names
PRPF6 C20orf14 Pre-mRNA-processing factor 6 Androgen receptor N-terminal domain-transactivating protein 1 PRP6 homolog U5 snRNP-associated 102 kDa protein
Molecular Weight(MW)
106925 Da
Function
Involved in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation
Tissue Specificity
Widely expressed.
Cellular Localization
Nucleus, nucleoplasm. Nucleus speckle. Note=Localized in splicing speckles
PRPF6 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PRPF6 antibody detected the PRPF6 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.