Application
PSCA Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the PSCA antibody detected the PSCA protein (arrow).Application
PSCA Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PSCA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PSCA Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PSCA; Prostate stem cell antigen |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PSCA Prostate stem cell antigen |
|---|---|
| Molecular Weight(MW) | 12912 Da |
| Function | May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro |
| Tissue Specificity | Highly expressed in prostate (basal, secretory and neuroendocrine epithelium cells). Also found in bladder (transitional epithelium), placenta (trophoblasts), stomach (neuroendocrine cells), colon (neuroendocrine cells) and kidney (collecting ducts). Overexpressed in prostate cancers and expression is correlated with tumor stage, grade and androgen- independence. Highly expressed in prostate cancer bone metastases Expressed in gastric epithelial cells, mainly in the isthmus (at protein level). Not detected in normal intestinal epithelium (at protein level) |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. |
Application
PSCA Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the PSCA antibody detected the PSCA protein (arrow).
Application
PSCA Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PSCA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
