Application
PRX Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PRX antibody detected the PRX protein (arrow).Application
PRX Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PRX Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PRX Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PRX; KIAA1620; Periaxin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1620 |
|---|---|
| Alternative Names | PRX KIAA1620 Periaxin |
| Molecular Weight(MW) | 154905 Da |
| Function | Seems to be required for maintenance of peripheral nerve myelin sheath. May have a role in axon-glial interactions, possibly by interacting with the cytoplasmic domains of integral membrane proteins such as myelin-associated glycoprotein in the periaxonal regions of the Schwann cell plasma membrane. May have a role in the early phases of myelin deposition |
| Tissue Specificity | Isoform 1 and isoform 2 are found in sciatic nerve and Schwann cells |
| Cellular Localization | Nucleus (By similarity). Isoform 2: Cytoplasm (By similarity). |
| Entrez Gene | 57716 |
|---|---|
| Nucleotide Accession | NP_870998.2 NP_066007.1 |
Application
PRX Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PRX antibody detected the PRX protein (arrow).
Application
PRX Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PRX Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
