PSMG2; HCCA3; PAC2; TNFSF5IP1; Proteasome assembly chaperone 2; Hepatocellular carcinoma-susceptibility protein 3; Tumor necrosis factor superfamily member 5-induced protein 1
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
HCCA3 PAC2 TNFSF5IP1
Alternative Names
PSMG2 HCCA3 PAC2 TNFSF5IP1 Proteasome assembly chaperone 2 Hepatocellular carcinoma-susceptibility protein 3 Tumor necrosis factor superfamily member 5-induced protein 1
Molecular Weight(MW)
29396 Da
Function
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization
Tissue Specificity
Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue
Western blot analysis of PSMG2 Antibody (C-term) in MDA-MB468 cell line lysates (35ug/lane). PSMG2 (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.