Application
Abgent invites you to submit your data (IHC, IF, IP, WB, FC) using this product. We will award you credits, 50% of the cost you paid, for future purchases. For availability of this promotion please contact us at tech@abgent.com.| Product Name | PTP epsilon Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PTPRE Receptor-type tyrosine-protein phosphatase epsilon |
|---|---|
| Molecular Weight(MW) | 80642 Da |
| Function | Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity) Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+) (By similarity) |
| Tissue Specificity | Expressed in giant cell tumor (osteoclastoma rich in multinucleated osteoclastic cells) |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cytoplasm. |
| Entrez Gene | 5791 |
|---|
Application
Abgent invites you to submit your data (IHC, IF, IP, WB, FC) using this product. We will award you credits, 50% of the cost you paid, for future purchases. For availability of this promotion please contact us at tech@abgent.com.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
