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PTPIA2 Antibody (N-term)

Catalog Number:OM219063
OM219063
Discount Price
OM219063-100ul
1~2 Week
100ul
OM219063-50ul
50ul
OM219063-20ul
20ul
1~2 Week
Product Profile
Product Name PTPIA2 Antibody (N-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms ICA3, ICA512
Alternative Names PTPRN
ICA3
ICA512
Receptor-type tyrosine-protein phosphatase-like N
Islet cell antigen 512
Islet cell autoantigen 3
PTP IA-2
Molecular Weight(MW) 105848 Da
Function Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2
Tissue Specificity Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary
Cellular Localization Membrane; Single-pass type I membrane protein. Note=Neuroendocrine secretory granules
Database Links
Entrez Gene 5798
Application

Application

The anti-PTPIA2 N-term Pab is used in Western blot to detect PTPIA2 in mouse pancreas tissue lysate.

Application

Formalin-fixed and paraffin-embedded human brain tissue reacted with PTPIA2 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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