Application
PTPN14 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the PTPN14 antibody detected the PTPN14 protein (arrow).| Product Name | PTPN14 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PEZ, PTPD2 |
|---|---|
| Alternative Names | PTPN14 PEZ Tyrosine-protein phosphatase non-receptor type 14 Protein-tyrosine phosphatase pez |
| Molecular Weight(MW) | 135261 Da |
| Function | Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell- matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial- mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Nucleus. Note=Translocation into the nucleus is associated with induction of cell proliferation. Partially colocalized with actin filaments at the plasma membrane |
| Entrez Gene | 5784 |
|---|---|
| Nucleotide Accession | NP_005392.2 |
Application
PTPN14 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the PTPN14 antibody detected the PTPN14 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
