Application
PTPRE Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PTPRE antibody detected the PTPRE protein (arrow).Application
PTPRE Antibody (N-term) (AP14405a)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPRE Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PTPRE Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PTPRE Receptor-type tyrosine-protein phosphatase epsilon |
|---|---|
| Molecular Weight(MW) | 80642 Da |
| Function | Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity) Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+) (By similarity) |
| Tissue Specificity | Expressed in giant cell tumor (osteoclastoma rich in multinucleated osteoclastic cells) |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cytoplasm. |
| Entrez Gene | 5791 |
|---|---|
| Nucleotide Accession | NP_569119.1 NP_006495.1 |
Application
PTPRE Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PTPRE antibody detected the PTPRE protein (arrow).
Application
PTPRE Antibody (N-term) (AP14405a)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPRE Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
