PVRL4 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PVRL4 antibody detected the PVRL4 protein (arrow).
PVRL4 LNIR PRR4 Poliovirus receptor-related protein 4 Ig superfamily receptor LNIR Nectin-4 Processed poliovirus receptor-related protein 4
Molecular Weight(MW)
55454 Da
Function
Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1. Does not act as receptor for alpha-herpesvirus entry into cells
Tissue Specificity
Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma
Cellular Localization
Cell membrane; Single-pass type I membrane protein (Potential). Cell junction, adherens junction Note=Colocalizes with MLLT4 at cadherin-based adherens junctions
PVRL4 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PVRL4 antibody detected the PVRL4 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.