Application
PUS10 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PUS10 antibody detected the PUS10 protein (arrow).| Product Name | PUS10 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CCDC139, DOBI |
|---|---|
| Alternative Names | PUS10 CCDC139 DOBI Putative tRNA pseudouridine synthase Pus10 Coiled-coil domain-containing protein 139 tRNA pseudouridine 55 synthase tRNA pseudouridylate synthase tRNA-uridine isomerase |
| Molecular Weight(MW) | 60244 Da |
| Function | Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death |
| Tissue Specificity | This PUS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human PUS10. |
| Entrez Gene | 150962 |
|---|---|
| Nucleotide Accession | NP_653310.2 |
Application
PUS10 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PUS10 antibody detected the PUS10 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
