Application
PYDC1 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PYDC1 antibody detected the PYDC1 protein (arrow).| Product Name | PYDC1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PYDC1; ASC2; ASCI; POP1; PYC1; Pyrin domain-containing protein 1; PAAD-only protein 1; Pyrin-only protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ASC2 ASCI POP1 PYC1 |
|---|---|
| Alternative Names | PYDC1 ASC2 ASCI POP1 PYC1 Pyrin domain-containing protein 1 PAAD-only protein 1 Pyrin-only protein 1 |
| Molecular Weight(MW) | 10107 Da |
| Function | Associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS |
| Tissue Specificity | Predominantly expressed in monocytes, macrophages and granulocytes |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 260434 |
|---|---|
| Nucleotide Accession | NP_690865.1 |
Application
PYDC1 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PYDC1 antibody detected the PYDC1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
